Anti Alzheimer Medicine in Pakistan
Afdol tablets are basically used for the treatment of Alzheimer disease. AGP pharmaceutical is preparing this anti-Alzheimer drug in Pakistan. It is available in two presentations i.e. Afdol 5mg and Afdol 10 mg in Pakistan.
Each 5 mg Afdol tablet contains Memantine HCl 5 mgEach 10 mg Afdol tablet contains Memantine HCl 10 mg.
Memantine (Afdol) is the first drug to be licensed for moderately severe to severe Alzheimer’s disease (AD). It is a N-methyl-D-aspartate (NMDA) receptor antagonist. Its mechanism of action differs from the other licensed treatments for AD, the acetylcholinesterase inhibitors, which are licensed for mild to moderate AD.
Afdol is indicated for the treatment of moderate to severe dementia of the Alzheimer’s type.
The recommended starting dose of Afdol is 5 mg once daily. The recommended target dose is 20 mg/day. The dose should be increased in 5 mg increments to 10 mg/day (5 mg twice a day), 15 mg/day (5 mg and 10 mg as separate doses), and 20 mg/day (10 mg twice a day). The minimum recommended interval between dose increases is one week.
- Afdol 5 mg tablets 10’s
- Afdol 10 mg tablets 56’s